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. Author manuscript; available in PMC: 2010 Jan 22.
Published in final edited form as: Lab Invest. 2008 Apr 21;88(6):579–590. doi: 10.1038/labinvest.2008.36

Figure 5. VEGF blockade and wound vascularity.

Figure 5

Immunohistochemical staining for PECAM was used to identify blood vessels in wounds from mice injected with goat IgG (a) or neutralizing anti-VEGF (b) antibodies 14 days post-wounding. The margins of the wound bed/scar are marked with arrows (scale bar = 100 μm). Blood vessel densities were determined and are represented graphically (c). The bars and lines represent means +/− S.E.M.; *p<0.0199, unpaired t-test; n = 6 for IgG and n = 5 for anti-VEGF for each dataset.