Table 3.
Histomorphometry Results of the Implants
| Scaffold | Cells | Porosity (%) | Scaffolds (with bone/total) | Bone (% of pore space) | |
|---|---|---|---|---|---|
| 1 | Blank | No cells | 77.4 ± 4.5a | 0/4 | 0 |
| 2 | BMPimpregnated | BMSCs | 1/8 | 0.0 ± 0.1 | |
| 3 | Mpsempty | No cells | 71.7 ± 1.7 | 0/8 | 0 |
| 4 | Mpsempty | BMSCs | 0/8 | 0 | |
| 5 | Mps-BMPlow | No cells | 73.1 ± 2.4 | 0/8 | 0 |
| 6 | Mps-BMPlow | BMSCs | 0/8 | 0 | |
| 7 | Mps-BMPhigh | No cells | 75.3 ± 2.2a | 5/8 | 2.9 ± 3.0 |
| 8 | Mps-BMPhigh | BMSCs | 6/8 | 2.7 ± 2.4 |
Scaffold porosity (mean ± SD), incidence of bone formation, and the percentage of bone area (mean ± SD) of the available pore space.
a
Significantly higher than Mpsempty and Mps-BMPlow (p < 0.05, ANOVA).
Mps, microparticles; BMP, bone morphogenetic protein-2; BMSCs, bone marrow stromal cells.