Table 3.
Examples of potential mAb targets based on need.
| Category | Target | Comments/concerns |
|---|---|---|
| Bioterrorism | Anthrax (B. anthracis) | Need for immediate dispersal upon exposure |
| Small pox (Variola virus) | Population of non-immune individuals | |
| Ebola virus | Highly virulent | |
| Emerging diseases | Henipavirus | Also potential bioterrorist agents |
| SARS-CoV | Possibility of recurrence of 2003 pandemic | |
| Influenza virus | H1N1 and H5N1 are pandemic threats | |
| Susceptible populations | Parainfluenza virus | LRI protection in at-risk pediatric populations |
| Candida spp. | Important class of nosocomial infection | |
| MDR bacteria | MRSA, VRSA | Increasing prevelance in community settings |
| Pseudomonas aeruginosa | Important class of nosocomial infection | |