Table 3.
Cell line | IC50 (µM) ± SD | IC50 (µM) ± SD |
---|---|---|
1 | 10i | |
SK-OV-3 | 0.0033 ± 0.0002 | 0.34 ± 0.01 |
SK-OV-3-MDR 1–6/6a | 0.0035 ± 0.0005 | 0.45 ± 0.01 |
Rrc | 1.8 | 1.3 |
HeLa | 0.0029 ± 0.0003 | 0.23 ± 0.03 |
WTβIIIb | 0.0033 ± 0.0008 | 0.27 ± 0.02 |
Rrc | 1.1 | 1.2 |
SK-OV-3-MDR 1–6/6 cells were generated from SK-OV-3 by adenoviral expression of MDR-1.
HeLa cells were transfected with the βIII tubulin isotype to generate the WTβIII cells.
The Rr values were calculated by dividing the IC50 of the genetically engineered line by the IC50 of the parental cell line.