Table 1.
0 d | 23 d | 23 d | 35 d | 35 d | 56 d | 56 d | |
---|---|---|---|---|---|---|---|
artesunate | artesunate | artesunate | |||||
Adult worms | 0 | 9.75 ± 0.96*** | 0 | 10.5±1.29*** | 0 | 10 ± 1.63*** | 0 |
Liver eggs (/g) | 0 | 0 | 0 | 26650.33 ± 1912.95*** | 0 | 51184.58 ± 1663.26*** | 0 |
Mice were percutaneously infected with S. japonicum; some were orally administered artesunate as described in Section 2. At 0 (before infection) and 23, 35, and 56 days postinfection, six mice from each group were sacrificed for worm burdens and eggs counts measurements. ***P < .001 compared to the artesunate groups at same time point.