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. 1998 Dec 22;95(26):15688–15693. doi: 10.1073/pnas.95.26.15688

Figure 3.

Figure 3

M. tb-9d8 infection partially protects immunocompromised mice without concomitant decrease in bacterial burden. (A) Survival of M. tb-9d8-infected GKO was not mediated through a reduction in lung cfu. Comparable cfu were recovered from GKO mice infected with M. tb-9d8 (•) or M. tb-3E5 (○), as well as M. tb-3E5-infected C57BL/6 mice (□) (n = 3 mice per group). (E) The 9d8 mAb did not affect extrapulmonary seeding of immunocompromised mice. GKO mice infected with M. tb-9d8 (•) yielded similar numbers of cfu as M. tb-3E5-infected GKO mice (○). GKO mice did, however, reveal increased numbers of cfu as compared with M. tb-3E5-infected C57BL/6 mice (□) (P < 0.05, Student’s t test) (n = 3 mice per group).