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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: J Investig Med. 2009 Dec;57(8):856–860. doi: 10.231/JIM.0b013e3181c5e61f

TABLE 1.

Integrin Expression in CFs in the Basal and Diseased Myocardium

αSubunit Subunit(s) Partner Ligand(s) Basal Adult Heart Failure (Relative to Basal Adult) Hypertension (Relative to Basal Adult)
α1 β1A, β3 LN, Col ++ = Decreased
α2 β1A LN, Col + = Decreased
α3 β1A LN, Col, FN + Not known Not known
α4 β1A FN, OPN +++ Not known Not known
α5 β1A FN, OPN +++ Decreased
α6 β1A LN + Not known Not known
α8 β1A FN, VN, OPN + Not known Not known
αV β1A, β3, β5 FN, VN, OPN + = Not known
β1A Not applicable Not applicable +++ Decreased Increased
β3 Not applicable Not applicable ++ Not known Not known
β5 Not applicable Not applicable + Not known Not known

Col indicates collagen; FN, fibronectin; LN, laminin; VN, vitronectin.