Table 3.
Univariable | Multivariable** | ||||
---|---|---|---|---|---|
Variable | PE | p | PE | p | Reliability*** |
Total ESV indexed to BSA1.3 (mL/m2) | −0.057 | 0.30 | 0.437 | 0.03 | 36% |
(Total ESV/BSA1.3)2 | −0.006 | 0.004 | 56% | ||
Total EDV indexed to BSA1.3 (mL/m2) | −0.006 | 0.87 | |||
Total stroke volume (mL) | 0.045 | 0.19 | |||
Total ejection fraction (per cent) | 0.075 | 0.43 | |||
Cardiac output (L/min) | 0.326 | 0.52 | |||
Total ventricular mass indexed to BSA1.3 (gm/m2) | −0.099 | 0.02 | |||
Total mass/EDV ratio (gm/mL) | −7.068 | 0.02 | −8.366 | 0.004 | 56% |
BSA, body surface area; EDV, end-diastolic volume; ESV, end-systolic volume; gm, grams; L, litres; m, meters; mL, milliliters; min, minute; PE, parameter estimate.
Parameter estimates represent the degree of change in the Summary Score associated with a one integer unit change in the laboratory testing variable.
Analysis limited to 155 subjects with values for the 7 variables. Missing values were not imputed.
R2=0.12 (R2 adjusted=0.11), p<0.001 (n=153). Final multivariable model includes a significant quadratic term for total end-systolic volume indexed to BSA1.3, indicating a non-linear relationship.
From bootstrap bagging (presented for the variables included in the multivariable model)