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. Author manuscript; available in PMC: 2010 Jan 25.
Published in final edited form as: J Pathol. 2003 Nov;201(3):343–354. doi: 10.1002/path.1446

Figure 2.

Figure 2

Histopathology of UIP (higher power). A hallmark of UIP is the heterogeneity, represented by dense, acellular bundles of collagen with smooth muscle metaplasia (arrow) in close approximation to the fibroblastic focus (FF), a dense collection of fibroblasts and myofibroblasts. Cuboidal epithelial cells lining distorted airspaces (which may be undergoing apoptosis) are seen overlying the fibroblastic focus