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. Author manuscript; available in PMC: 2010 Jan 25.
Published in final edited form as: Cardiovasc Res. 2007 Dec 7;78(1):185–196. doi: 10.1093/cvr/cvm093

Figure 6.

Figure 6

(A) Images of macrophages from apoE°, °CD36°/apoE°, SRA°/apoE°, and CD36°/SRA°/apoE° mice after 10 days in culture (× 100 magnification). Macrophages from apoE° mice showed the greatest degree of spreading, and those from CD36°/SRA°/apoE° showed the least. (B) The results from modified Boyden chamber migration assays. Macrophages from apoE° mice showed the most robust migration in response to 10 ng/mL MCP-1. In comparison, macrophages from CD36°/apoE° and CD36°/SRA°/apoE° demonstrated a significant decrease in migration. Macrophages isolated from all four groups were significantly inhibited in their migration to MCP-1 when co-cultured with 50 µg/mL oxLDL.