Table 2.
Risk estimates for BPDE-induced 3p deletions in patients with RCC and healthy controls
| No. (%) |
Adjusted OR (95% CI)* | ||
|---|---|---|---|
| Cases | Controls | ||
| 3p25.2 | |||
| Low sensitivity | 44 (34.1) | 49 (47.6) | 1 |
| High sensitivity† | 85 (65.9) | 54 (52.4) | 2.02 (1.18–3.46) |
| 3p21.3 | |||
| Low sensitivity | 44 (29.7) | 50 (46.3) | 1 |
| High sensitivity† | 104 (70.3) | 58 (53.7) | 2.28 (1.33–3.92) |
| 3p14.2 | |||
| Low sensitivity | 43 (31.9) | 48 (45.3) | 1 |
| High sensitivity† | 92 (68.1) | 58 (54.7) | 1.84 (1.07–3.16) |
| 3p12.2 | |||
| Low sensitivity | 41 (29.9) | 50 (46.7) | 1 |
| High sensitivity† | 96 (70.1) | 57 (53.3) | 1.97 (1.15–3.37) |
| 3q13 (control) | |||
| Low sensitivity | 40 (41.7) | 43 (40.5) | 1 |
| High sensitivity† | 56 (58.3) | 63 (59.5) | 0.92 (0.51–1.67) |
*
Odds ratio (OR) adjusted for age (as a continuous variable), gender, ethnicity, and smoking status; data are means and 95% confidence intervals (CI)
†
Categorized at the median value of deletions in the control group
Not all patients and controls had completed analysis for deletions at each locus