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. 2009 Aug 26;1(3):e00015. doi: 10.1042/AN20090008

Figure 2. Acute astroglial loss from ischaemic microvessels.

Figure 2

In intact spinal grey matter, Aqp-4- and GFAP-immunoreactive astrocytic endfeet are associated with perfused microvessels (A–D; arrowheads). By 3 h post-ischaemia, significant loss of GFAP-immunoreactivity is observed in affected tissue (E), with no detectable Aqp-4 staining associated (F) with microvascular elements (G). By 6 h post-ischaemia, all GFAP- (I) and Aqp-4- (J) immunoreactivity is lost in affected grey matter, despite a preservation of intact microvessels (K and L). Scale bar = 50 μm (C–F).