Table 4.
Summary of ex-vivo animal studies
| Ref | Tissue | Challenge | Outcome |
|---|---|---|---|
| 3 | Excised canine larynges | Dehydration of excised vocal folds by immersion in a 25% sucrose solution | ↑ Stiffness |
| ↑ Viscosity | |||
| ↑ Damping ratio | |||
| Rehydration of excised vocal folds through immersion in dH20 | ↓ Stiffness | ||
| ↓ Viscosity | |||
| ↓ Damping ratio | |||
| 5 | Excised canine larynges | Dehydration of vocal folds by exposure to dry air | ↑ PTP |
| ↑ Glottal airflow | |||
| ↓ (Slight) Sound intensity | |||
| ↓ Vocal efficiency | |||
| Rehydration of vocal folds by immersion in a saline solution | ↑ PTP | ||
| ↓ Glottal airflow | |||
| ↑ (Slight) Sound intensity | |||
| ↑ Vocal efficiency | |||
| 6 | Excised canine larynges | Dehydration of vocal folds by exposure to dry air | ↑ PTP |
| ↑ Glottal airflow | |||
| ↓ Sound intensity | |||
| ↓ Vocal efficiency | |||
| 31 | Excised ovine larynges | Dehydration of vocal folds by exposure to dry air (0% humidity) | ↑ Stiffness |
| ↑ Viscosity | |||
| Hydration of vocal folds by exposure to humid air (100% humidity). | ↑ Stiffness to a lesser extent | ||
| ↑ Viscosity to a lesser extent | |||