TABLE 3.
Cognitive decline (change scores) within and between the two groups
APOE ε4 Carriers (N=20) | APOE ε4 Within-Group (t[df]; p) | Non-APOE ε4 Carriers (N=29) | Non-APOE ε4 Within-Group (t[df]; p) | Between-Group (t[df]; p) | |
---|---|---|---|---|---|
BFR | −14.4 (18.9)** | −3.4[19]; 0.003 | −4.2 (12.5) | −1.8[28]; 0.08 | 2.1[47]; 0.03* |
Rey copy | −1.9 (4.9)** | −3.3[19]; 0.004 | −2.9 (5.1)** | −3.6[28]; 0.001 | −0.7[47]; 0.5 |
Rey delayed recall | −2.2 (3.1) | −1.7[19]; 0.1 | −2.4 (3.6)** | −3.1[28]; 0.005 | −0.16[47]; 0.9 |
CFL | 1.3 (9.4) | 0.6[19]; 0.5 | 2.0 (8.1) | 1.3[28]; 0.18 | 0.29[47]; 0.8 |
BNT | −2.2 (8.3) | −1.2[19]; 0.2 | −0.7 (1.5)* | −2.3[28]; 0.03 | 0.8[19.9]; 0.4 |
Note: Values are mean (standard deviation), unless otherwise indicated.
BFR: Buschke-Fuld Selective Reminding, Total Score, a measure of verbal memory;30 Rey copy: Rey-Osterrieth Complex Figure, Copy, a measure of visuospatial functioning;31 Rey delayed: Rey-Osterrieth Complex Figure, Delayed Recall,31 a measure of nonverbal memory; CFL: test of verbal fluency;32 BNT: Boston Naming Test, a measure of naming.33
p<0.05 within-or between-group comparisons in the test change scores;
p<0.01 within-or between-group comparisons in the test change scores.