Table 1.

Review of the unbalanced karyotypes resulting from different segregation patterns in the carriers of t(11;22)

Karyotype	Segregation	Outcome	Reference
47,XX/XY,+der(22)t(11;22)(q23;q11.2)	3 : 1	der(22) syndrome	Zackai and Emanuel (1980); Shaikh et al. (1999)
47,XX,+der(22)t(11;22)(q23;q11.2)	2 : 2 adjacent-1(pat. de novo) + mat. MI nondisjunction of chr 22	der(22) syndrome	Dawson et al. (1996)
47,XX/XY,t(11;22)(q23;q11.2)pat, +der(22)	? 2 : 2 alternate + MII or postzygotic nondisjunction of der(22)	der(22) syndrome	Lockwood et al. (1989); Abeliovich and Carmi (1990); Lurie and Podelschuk (1992); Simi et al. (1992)
47,XX,t(11;22)(q23;q11.2)pat,+der(22)	Crossover within chr 22 + 3 : 1 segregation	der(22) syndrome	Petkovic et al. (1996)
46,XX,der(22)t(11;22)(q23;q11.2)pat	2 : 2 adjacent-1	Empty sac (one of triplets)	Soler et al. (1993)
46.XY,der(22)t(11;22)(q23;q11.2)mat/46,XY	2 : 2 or 3 : 1 with multiple postzygotic errors	26 year old with moderate mental retardation	Kulharya et al. (2002)
45,XY,der(11)t(11;22)(q23;q11.2)mat,−22	3 : 1	Embryonic death at 7 weeks.	This report