Table 1.
Equilibrium dissociation constants for binding of UvrA and human NER proteins to TG-51-bp and AAF-50-bp DNA substrates at 30°Ca
Protein | Kd for TG-51 bp (nM) | Kd for AAF-50 bp (nM) |
---|---|---|
UvrA | 24 ± 2 | 10 ± 1 |
XPAb | 48 ± 4 | 44 ± 6 |
XPC/HR23B | 18 ± 2 | 27 ± 3 |
aData represent the means ± SD of three experiments.
bFor XPA the dissociation constants were determined for XPA dimers.