Figure 1. The absence of Itk affects the development of CD4 and CD8 T cells.

(A) Thymocytes from WT or Itk^−/− mice were analyzed for expression of CD4 and CD8 (left), or gated first on the TCR^hi population and analyzed for CD4 and CD8 (right). (B) The number of thymocytes (total, left) or TCR^hi thymocytes (right) in WT and Itk^−/− mice. *p<0.05, n = 3–5 mice.