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. 2010 Jan 26;5(1):e8891. doi: 10.1371/journal.pone.0008891

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Hu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) CD4⁺/transgene TCR⁺ splenocytes from OT-II, OT-II/Itk^−/−, DO11.10 and DO11.10/Itk^−/− mice were analyzed for CD44 and CD62L. (B) The percentages of TCR transgene, CD4, CD44^hi and CD62L^lo T cells for each genotype is indicated. p<0.05, n = 3–5. (C) The number of TCR transgene, CD4⁺CD62L^loCD44^hi as well as CD4⁺CD62L^hiCD44^lo T cells for each genotype is indicated.