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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Am J Obstet Gynecol. 2009 Oct 4;202(1):77.e1–77.e9. doi: 10.1016/j.ajog.2009.07.058

TABLE 3.

Groups and Exposures

Surgical Controls
(IA + IT Saline)
Lung
(IA Saline + IT LPS)
Amniotic Fluid + Gut
(IA LPS + IT Saline)
Amniotic Fluid
(IA LPS + IT Saline + Eso Lig)

Fetal Thymus
Weight/body weight (g/kg) - 2d 1.38±0.09 1.19+0.21 1.27±0.14 1.61±0.20
  7d - 1.39±0.12 1.02±0.19 1.44±0.19
CD4 Cells (%) - 2d 22.3±10.3 39.7±12.5* 26.9±12.6 23.6±10.7
  7d - 46.5±13.3* 49.6±9.8* 53.7±12.2*
CD8 Cells (%) - 2d 14.5±10.7 29.3±12.5* 29.5±12.4* 30.9±16.1*
  7d - 40.5±20.2* 39.4±10.3* 53.9±16.6*
Fetal Posterior Mediastinal
Lymph Node
Weight/body weight (g/kg) - 2d 0.19±0.05 0.31±0.04* 0.22±.034 0.16±0.01
  7d - 0.33±0.02* 0.33±0.04* 0.26±0.04
CD4 Cells (%) - 2d 12.1±4.6 27.4±7.9* 26.9±12.6* 37.2±12.9*
  7d - 29.6±8.4* 49.6±9.8* 48.6±17.2*
CD8 Cells (%) - 2d 9.4±3.2 32.7±16.8* 25.5±11.4* 31.5±15.2*
  7d - 44.8±19.3* 44.7±21.2* 39.6±18.2*

IA - Intra-amniotic Infusion; IT - Intratracheal Infusion; Eso Lig. - Esophageal Ligation

*

p<0.05 vs. surgical controls