Table 2.

 Relative risk of myocardial infarction and stroke in patients receiving various two drug antihypertensive regimens that included a diuretic

	Myocardial infarction				Stroke
	Cases	Controls	Odds ratio (95% CI)		Cases	Controls	Odds ratio (95% CI)
Minimally adjusted*
Diuretics and β blockers	93	459	Ref		77	459	Ref
Diuretics and calcium channel blockers	68	174	1.93 (1.34 to 2.77)		31	174	1.00 (0.62 to 1.61)
Diuretics and angiotensin converting enzyme inhibitors or angiotensin receptor blockers	50	319	0.78 (0.53 to 1.13)		34	319	0.71 (0.46 to 1.10)
Fully adjusted†
Diuretics and β blockers	93	459	Ref		77	459	Ref
Diuretics and calcium channel blockers	68	174	1.98 (1.37 to 2.87)		31	174	1.02 (0.63 to 1.64)
Diuretics and angiotensin converting enzyme inhibitors or angiotensin receptor blockers	50	319	0.76 (0.52 to 1.11)		34	319	0.71 (0.46 to 1.10)
Thiazides only†
Diuretics and β blockers	83	434	Ref		65	434	Ref
Diuretics and calcium channel blockers	59	152	2.08 (1.41 to 3.09)		24	152	1.02 (0.60 to 1.75)
Diuretics and angiotensin converting enzyme inhibitors or angiotensin receptor blockers	45	291	0.81 (0.54 to 1.21)		29	291	0.75 (0.47 to 1.19)
Index year ≥1994†
Diuretics and β blockers	67	315	Ref		57	315	Ref
Diuretics and calcium channel blockers	45	113	1.95 (1.24 to 3.08)		23	113	1.10 (0.63 to 1.94)
Diuretics and angiotensin converting enzyme inhibitors or angiotensin receptor blockers	40	254	0.74 (0.48 to 1.14)		30	254	0.77 (0.47 to 1.24)

*Adjusted for age, sex, and index year.

†Adjusted for age, sex, index year, smoking, and total cholesterol.