Skip to main content
. 2010 Jan 25;340:c103. doi: 10.1136/bmj.c103

Table 4.

 Relative risk of myocardial infarction and stroke in patients receiving various two drug antihypertensive regimens that included a diuretic*†

Myocardial infarction Stroke
Cases Controls OR (95% CI) Cases Controls OR (95% CI)
Diuretic and atenolol 68 354 Ref 54 354 Ref
Diuretic and verapamil 35 92 2.24 (1.33 to 3.77) 14 92 1.01 (0.50 to 2.02)
Diuretic and felodipine 14 28 2.38 (1.16 to 4.89) 5 28 1.09 (0.36 to 3.33)
Diuretic and lisinopril 46 292 0.81 (0.54 to 1.22) 27 292 0.64 (0.39 to 1.05)

*76% of patients treated with β blockers received atenolol; 52% of patients treated with calcium channel blockers received verapamil and 17% received felodipine; 91% of patients treated with angiotensin converting enzyme inhibitors or angiotensin receptor blockers received lisinopril.

†Adjusted for age, sex, index year, smoking, and total cholesterol.