Table 3.
Parameter estimates for the toxicological parameters, resulting from the model fits of Fig. 3, with 95% likelihood-based confidence intervals
| Symbol | Parameter | Pyrene | Fluoranthene |
|---|---|---|---|
| k e | Elimination rate constant | 0.195 (0.142–0.288) d−1 | 0.0842 (0.0513–0.120) d−1 |
| W | Weight factor | 1 (n.e.) | 1.10 (0.896–1.54) |
| c 0s | NEC for survival | 0.386 (0.341–0.428) μM | |
| b | Killing rate | 2.53 (1.77–3.66) μM−1 d−1 | |
| h | Blank hazard rate | 0.0134 (0.00960–0.0184) d−1 | |
| c 0 | NEC for reproduction costs | 0.128 (0.114–0.140) μM | |
| c T | Tolerance for reproduction costs | 0.0160 (0.0126–0.0189) μM | |
| c 0 | NEC for growth costs | 0.186 × 10−3 (0–0.134) μM | |
| c T | Tolerance for growth costs | 0.833 (0.696–1.02) μM | |
For the additional effect on growth costs, instantaneous steady state of the relevant internal concentration is assumed