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. Author manuscript; available in PMC: 2010 Jan 26.
Published in final edited form as: J Appl Physiol (1985). 2007 Aug 30;103(5):1678–1687. doi: 10.1152/japplphysiol.00420.2007

Fig. 1.

Fig. 1

Influence of calcineurin B (PPP3R1) insertion-deletion (I/D) × insulin-like growth factor 1 (IGF1) cytosine adenine (CA) repeat genotype groups on change in 1-repetition maximum (1 RM) strength with strength training (ST). There was a trend for a significant gene × gene interaction between IGF1 CA repeat and PPP3R1 I/D (P = 0.072). Individuals homozygous for PPP3R1 II who were also heterozygous for IGF1 192 allele had significantly greater increases in 1 RM strength with ST than individuals homozygous for PPP3R1 II who were also IGF1 noncarriers of the 192 allele (*P = 0.003). Values are covaried for age, hormone replacement therapy status and sex, race, height, body mass index, and baseline 1 RM strength. Values are means ± SE.