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A, the number of intestinal tumors that developed in p27+/+, p27+/−, or p27−/− mice fed on standard chow diet, AIN-76A, or Western-style diet for 36 weeks. Incidence (B), frequency (C), and size (D) of intestinal tumors in the Apc+/−,p27+/+, Apc+/−,p27+/−, or Apc+/−,p27−/− mice fed AIN-76A diet or western-style diet for 16 weeks. *, P < 0.05; **, P < 0.01.
