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. Author manuscript; available in PMC: 2010 Jan 26.
Published in final edited form as: Biochem Soc Trans. 2008 Dec;36(Pt 6):1472–1477. doi: 10.1042/BST0361472

Table 1. Galectin–glycoprotein lattices that regulate cell functions.

Shown are galectin receptor glycoproteins that have been proposed to participate in lattice formation. This does not constitute a comprehensive list of galectin-binding glycoproteins. DPPIV, dipeptidyl peptidase IV; gp114, glycoprotein 114; MUC1, mucin 1.

Galectin Cell types affected Glycoprotein receptors Functions References
1 T-cells, thymocytes CD3/TCR, CD7, CD43, CD45 Apoptosis, regulate antigen response [2329]
3 MDCK (renal epithelia), intestinal enterocytes, T-cells, carcinoma cells MUC1, LPH, p75, gp114, DPPIV, TCR, EGFR Stabilize apically targeted vesicles, regulate response to antigen, inhibit growth factor receptor endocytosis [4,11,19,20,3538,44]
4 Intestinal cell microvilli, HT-29 5M12 (enterocyte-like cells) Alkaline phosphatase, aminopeptidase N Lipid raft stabilization, lipid raft-dependent apical targeting [15,21]
9 Osteoblasts, pancreatic β-cells Glut2 Lipid raft stabilization, inhibit Glut2 endocytosis [16,46]
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