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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Obesity (Silver Spring). 2009 Jun 4;18(1):35–41. doi: 10.1038/oby.2009.176

Figure 4.

Figure 4

A HF diet increases (A) plasma concentrations of SAA. Data represent the mean ± SEM (n = 22 – 26 mice/group). *, denotes P = 0.01. (B) IEF demonstrates that both SAA 1.1 and 2.1 expression are increased in plasma from mice fed a HF diet. Shown are representative blots with each lane representing one mouse from each group. (C) Immunoblot analysis demonstrates that SAA is highly associated with plasma VLDL and LDL in mice fed a HF diet. Shown are representative blots from one mouse from each group. Lanes were loaded with equal aliquots of (B) plasma and (C) FPLC fractions. (D) Immunocytochemistry demonstrates SAA co-localizes with biglycan and apoB. Shown are representative adjacent sections from an atherosclerotic lesion from an apoE−/− mice fed a HF diet. (200× magnification).