On the day before the appearance of lesion (Day 0), HSV shedding was present at 107 copies/ml in the perianal area, and also on the right labia majora and left labia minora at 102 copies/ml. On Day 1, the lesion appeared, shedding was detected at all of the sampled sites, with highest level of shedding at the site of lesion. In the following days, shedding from the lesion persisted, at decreasing copy number each day. HSV shedding continued after the perianal lesion healed for an additional 2 days (data not shown).
no HSV DNA detected 2-3 log10copies/ml HSV DNA detected, 3-4 log10copies/ml HSV DNA detected, site of lesion, with log10copies/ml HSV DNA detected.
L=left, R=right. MJ=Labia majora, MN=labia minora, PA=perianal, URE=urethra.
Numbers represent log10 copy number/ml detected.