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. 2009 Jul 11;3(3):186–194. doi: 10.1007/s12105-009-0126-1

Fig. 4.

Fig. 4

Examples of HR HPV-ISH and p16 immunohistochemistry results. a HR HPV positive (blue nuclear dots) tumor by ISH (×600). b HR HPV negative tumor by ISH (×600). c p16 positive tumor by immunohistochemistry showing strong nuclear and cytoplasmic staining (×400). d p16 negative tumor by immunohistochemistry (×400)