Table 1.
Clinical Characteristics of Patients with Oropharyngeal Carcinoma by Histologic Type, Fisher’s exact test and t-test
| Histologic type (#) | K SCC (29) | NK SCC (55) | Hybrid SCC (34) | Total (118) |
|---|---|---|---|---|
| Age (Mean ± SD) | 58.8 (±9.2) | 54.0 (±8.4) | 57.1 (±8.4) | 56.1 (±9.5) |
| P value | – | 0.0265 | NS | |
| Sex (%) | ||||
| Male | 23 (79.3) | 53 (96.4) | 27 (79.4) | 103 (87.3) |
| Female | 6 (20.7) | 2 (3.6) | 7 (20.6) | 15 (12.7) |
| P value | 0.018 | – | 0.024 | |
| Smoker (%) | ||||
| Yes | 17 (58.6) | 30 (54.5) | 17 (50.0) | 64 (54.2) |
| No | 3 (10.3) | 10 (18.2) | 6 (17.6) | 19 (16.1) |
| Unknown | 9 (31.0) | 15 (27.3) | 11 (32.4) | 35 (29.7) |
| P value | – | NS | NS | |
| Stage (%) | ||||
| II | 5 (17.2) | 2 (3.6) | 1 (2.9) | 8 (6.8) |
| III | 6 (20.7) | 11 (20.0) | 6 (17.6) | 23 (19.5) |
| IVA | 17 (58.6) | 40 (72.7) | 23 (67.6) | 80 (67.8) |
| IVB | 1 (3.4) | 2 (3.6) | 4 (11.8) | 7 (5.9) |
| P value | – | NS | NS | |
| Lymph node metastases (%) | ||||
| Yes | 11 (37.9) | 39 (70.9) | 16 (47.1) | 66 (55.9) |
| No | 12 (41.4) | 14 (25.5) | 16 (47.1) | 42 (35.6) |
| Unknown | 6 (20.7) | 2 (3.6) | 2 (5.8) | 10 (8.5) |
| P value | 0.038 | – | 0.036 | |
| IMRT (%) | ||||
| Definitive | 14 (48.3) | 8 (14.5) | 12 (35.3) | 34 (28.8) |
| Post-operative | 14 (48.3) | 46 (83.6) | 20 (58.8) | 80 (67.8) |
| Both | 1 (3.4) | 1 (1.8) | 2 (5.9) | 4 (3.4) |
| P value | P = 0.003 | – | P = 0.017 | |
| Chemotherapy (%) | ||||
| Yes | 11 (37.9) | 18 (32.7) | 11 (32.4) | 40 (33.9) |
| No | 18 (62.1) | 37 (67.3) | 23 (67.6) | 78 (66.1) |
| P value | – | NS | NS | |
K SCC keratinizing squamous cell carcinoma, NK SCC nonkeratinizing squamous cell carcinoma, Hybrid SCC hybrid squamous cell carcinoma, IMRT intensity-modulated radiation therapy, NS not significant