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. 2009 Dec 15;12(1):98–106. doi: 10.1208/s12248-009-9165-5

Table VIII.

Confirmation of the Specificity of the IgG4 Type Anti-CHO-HCP Antibody in Normal Human Serum (HS) Samples—Uncoated Plate Specificity Testing

Human serum Mean OD Reported as
Coated Uncoated
HS-8 2.517 0.121 Positive/Specific
HS-41 0.573 0.598 Positive/Non-specific
HS-43 0.477 0.144 Positive/Specific
HS-6a 0.127 0.147 Negative
HS-23a 0.080 0.071 Negative
HS-63a 0.119 0.124 Negative
HS-B13a 0.094 0.084 Negative
HS-B14a 0.079 0.081 Negative

Samples were analyzed on the CHO-HCP-coated and uncoated plates using the biotin mouse anti-human IgG4 antibody detector in conjunction with avidin-D-HRP

aTested negative for anti-CHD-HCP reactivity