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. 2009 Nov 19;12(1):33–43. doi: 10.1208/s12248-009-9157-5

Fig. 1.

Fig. 1

Movement of molecules from blood to body tissues. In general, the rate of distribution may be limited by blood flow (perfusion-rate limited, a) or the membrane permeability (permeability-rate limited, b). Mechanisms of transvascular transport: convection, due to the pressure gradient (c), and diffusion, primarily due to the concentration gradient (d)