Fig 5.

Effects of γ-globin expression on red blood cell histology. Wright–Giemsa stained peripheral blood smears from individual animals are presented, including wild-type C57BL/6J, non-transgenic β-thalassaemia intermedia Hbb^th–3/+ (Thal) or Hbb^th–3/+ individuals containing one copy of the γ^lo transgene allele (γ^lo/−), two copies of the γ^lo transgene allele (γ^lo/γ^lo) or two copies of the γ^hi transgene allele (γ^hi/γ^hi) (original magnification ×60).