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. Author manuscript; available in PMC: 2010 Jan 26.
Published in final edited form as: Br J Haematol. 2006 Jul;134(1):100–108. doi: 10.1111/j.1365-2141.2006.06102.x

Fig 6.

Fig 6

Effects of γ-globin expression on survival of mice transplanted with Hbbth–3/Hbbth–3 fetal liver cells (FLCs). FLCs were collected from day 15.5 homozygous Hbbth–3/Hbbth–3 fetuses containing either no transgenes or two copies of either the γlo of γhi transgene alleles (γlo/γlo or γhi/γhi respectively). These cells were mixed in different ratios (shown as the percentage of transgenic FLCs), and transplanted into myeloablated congenic C57BL/6J recipients. Transplant recipients were monitored closely and killed when moribund or severely anemic with hematocrits <15%. (A) Survival of recipients transplanted with mixtures of γlo/γlo FLCs. (B) Survival of recipients transplanted with mixtures of γhi/γhi FLCs. *P ≤ 0.01 vs. 0% controls.