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. 2009 Dec 30;6:42. doi: 10.1186/1742-2094-6-42

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Copyright ©2009 Rupprecht et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Migration of B cells to CSF samples. (A) migration index of CD19⁺B cells to CSF samples from different patient groups, horizontal bars represent the mean value, *: p < 0.001. (B) and (C) exemplary result of a FACS analysis of (B) migrated or (C) not-migrated CD19⁺CD27⁺B cells towards the CSF sample of a LNB patient. (D) percentage of migrated vs. not-migrated CD27⁺CD19⁺B cells, using either CSF-samples of patients with LNB (n = 3) or 500 ng/ml rhCXCL13 (mean of two independent experiments, done in duplicate) as chemotactic agents.