Fig. 1.

Termination of KA-induced SE by diazepam, 3 h after its onset, does not reduce neuronal degeneration in the hippocampus during epileptogenesis. Nissl-stained (a) and Fluoro-Jade C-stained (b) sections demonstrating hippocampal subfields. The CA1, CA3, and hilus regions are shown at higher magnification in c. There was no significant difference in the number of the irreversibly degenerating cells between the group that was administered diazepam (KA +DZP group) 3 h after the onset of SE, and the group that was not treated with diazepam (KA group). Staining in this example was performed 7 days after SE. Scale bar 300 μm