Table 3.
Score | Cutoff | % |
Significant fibrosis (F2-4) |
|||||
Sen | Spe | PPV | NPV | +LR | -LR | |||
APRI | < 0.50 | 27 | 0.84 | 0.35 | 0.47 | 0.76 | 1.29 | 0.46 |
> 1.50 | 32 | 0.47 | 0.80 | 0.62 | 0.69 | 2.35 | 0.66 | |
FIB-4 | < 1.45 | 65 | 0.63 | 0.85 | 0.74 | 0.76 | 4.20 | 0.44 |
> 3.25 | 13 | 0.25 | 0.96 | 0.80 | 0.65 | 6.25 | 0.78 | |
Forn’s index | < 4.20 | 46 | 0.75 | 0.63 | 0.59 | 0.78 | 2.03 | 0.40 |
> 6.90 | 18 | 0.34 | 0.96 | 0.85 | 0.68 | 8.50 | 0.69 | |
Hepascore | < 0.50 | 23 | 0.88 | 0.50 | 0.55 | 0.85 | 1.74 | 0.26 |
> 0.84 | 27 | 0.50 | 0.91 | 0.80 | 0.72 | 5.56 | 0.55 | |
SLFG | < 3.00 | 23 | 0.91 | 0.33 | 0.48 | 0.83 | 1.36 | 0.27 |
> 8.70 | 22 | 0.47 | 0.96 | 0.88 | 0.72 | 11.75 | 0.55 |
Sen: Sensitivity; Spe: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.