Table 3.
Distribution of the IL-10 promoter polymorphisms among trauma patients
| Loci | Patients | n | MA (%) | Genotypes, n (%) | HWE | ||
|---|---|---|---|---|---|---|---|
| wild | heterozygous | variant | |||||
| A-1082G | All | 308 | 15.4 | 224 (72.7) | 73 (23.7) | 11 (3.6) | 0.11 |
| Sepsis | 147 | 12.2 | 115 (78.2) | 28 (19.1) | 4 (2.7) | ||
| Non-sepsis | 161 | 18.3a | 109 (67.7)b | 45 (28) | 7 (4.3) | ||
| T-819C | All | 308 | 29.2 | 157 (51.0) | 122 (39.6) | 29 (9.4) | 0.46 |
| Sepsis | 147 | 29.3 | 73 (49.7) | 62 (42.2) | 12 (8.2) | ||
| Non-sepsis | 161 | 29.2 | 84 (52.2) | 60 (37.3) | 17 (10.6) | ||
| A-592C | All | 307 | 34.0 | 141 (45.9) | 123 (40.1) | 43 (14.0) | 0.07 |
| Sepsis | 147 | 34.4 | 65 (44.2) | 63 (42.9) | 19 (12.9) | ||
| Non-sepsis | 160 | 33.8 | 76 (47.5) | 60 (37.5) | 24 (15.0) | ||
Sepsis vs. non-sepsis: aP = 0.037, bP = 0.038. HWE = Hardy-Weinberg equilibrium; MA = minor allele.