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. 2009 Nov 26;13(6):R188. doi: 10.1186/cc8182

Table 5.

Clinical relevance of Interleukin-10 haplotypes in major trauma patients

Haplotype* Count IL-10 (pg/ml) MODS Sepsis (%)
0(ATA) 71 72.18 ± 22.51 4.25 ± 2.60 28 (39.4)
1(ATA) 157 65.19 ± 20.36 5.00 ± 2.89 76 (48.4)
2(ATA) 79 60.27 ± 19.24a, c 4.24 ± 2.39 43 (54.4)

*'0 ATA haplotype' includes the following genotypes: ATC/ATC, ATC/ACC, ACA/ACA, ACA/ACC, ACC/ACC, ATC/GTC, ATC/GCC, ACC/GTC, ACA/GCA, ACC/GCA, ACA/GCC, ACC/GCC, GTA/GTC, GTC/GTC, GTA/GCC and GTC/GCA; '1 ATA haplotype' includes ATA/ATC, ATA/ACA, ATA/ACC, ATA/GTA, ATA/GTC, ATA/GCA and ATA/GCC; '2 ATA haplotype' is ATA/ATA. haplotype is indicated in an order of -1082A, -819T and -592A.

a: 2 ATA vs 0 ATA, P = 0.041; c: haplotype dose effect, P = 0.041.

MODS = multiple-organ dysfunction syndrome.