Table 1.
Clinical characteristics of patients with sepsis due to VAP (n = 36) and sepsis caused by other infections (n = 32).
| VAP | Other infections | P | |
|---|---|---|---|
| Male/female | 23/13 | 14/18 | 0.099 |
| Age (years) | 68.88 (15.57) | 64.41 (19.76) | 0.300 |
| Sepsis/severe sepsis/septic shock | 7/22/7 | 15/7/10 | 0.411 |
| APACHE II score | 18.25 (4.31) | 15.33 (5.03) | 0.200 |
| WBCs (/μl) | 11530 (1179) | 14530 (1469) | 0.141 |
| Monocytes | 234 (149) | 311 (49) | 0.422 |
| Lymphocytes | 629 (896) | 685 (172) | 0.922 |
| Neutrophils | 8299 (1342) | 9180 (1371) | 0.642 |
| Use of steroids (n, %) | 12 (33.33) | 13 (28.12) | 0.501 |
| Comorbidities (n, %) | |||
| COPD | 9 (25.00) | 3 (9.38) | 0.083 |
| DM | 9 (25.00) | 6 (18.75) | 0.439 |
| CHF | 3 (8.33) | 7 (21.87) | 0.206 |
| CRF | 4 (11.11) | 2 (6.25) | 0.414 |
| Prior infections (n) | 2 | 1 | |
| Number of failing organs (n) | |||
| Two or more | 8 | 11 | |
| Duration of hospitalization (days) | 18.93 (20.84) | 19.04 (27.90) | 0.151 |
| Duration of mechanical ventilation (days) | 18.34 (21.11) | 26.76 (29.1) | 0.525 |
| Bacterial causes (n, %) | |||
| P. aeruginosa | 12 (33.33) | 4 (12.50) | |
| A. baumannii | 7 (19.44) | 5 (15.62) | |
| K. pneumoniae | 3 (8.33) | 5 (15.62) | |
| E. coli | 1 (2.77) | 5 (15.62) | |
| Ent. cloacae | 2 (5.55) | 2 (6.25) |
Values are expressed as means (standard deviation).
APACHE = Acute Physiology and Chronic Health Evaluation; CHF = congestive heart failure; CRF = chronic renal failure; COPD = chronic pulmonary obstructive disease; DM = diabetes mellitus; VAP = ventilator-associated pneumonia; WBCs = white blood cells.