Table 2.
Risk factors of hypotension during connection of CRRT in children
| Hypotension | No hypotension | P | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age (months) | 53.4 | 67.5 | 50.0 | 61.4 | 0.694 |
| Weight (kg) | 18.1 | 19.8 | 16.9 | 17.3 | 0.910 |
| PRISM score | 16.8 | 15.5 | 21.6 | 25.8 | 0.650 |
| PIM score | 10.1 | 13.4 | 10.9 | 16.8 | 0.874 |
| PELOD score | 25.7 | 30.2 | 20.7 | 22.7 | 0.294 |
| Number of failed organs | 3.2 | 1.2 | 2.8 | 1.1 | 0.139 |
| Lactic acid (mmol/L) | 3.2 | 3.3 | 3.0 | 3.8 | 0.357 |
| Arterial pH | 7.32 | 0.12 | 7.31 | 0.10 | 0.341 |
| MAP (mmHg) | 58.2 | 14.8 | 62.9 | 20.2 | 0.124 |
| Dose of adrenaline (μg/kg/min) | 0.4 | 0.5 | 0.57 | 1.3 | 0.734 |
| Dose of dopamine (μg/kg/min) | 9.1 | 6.6 | 9.0 | 6.6 | 0.932 |
| Initial creatinine (mg/dL) | 1.4 | 1.1 | 1.5 | 1.3 | 0.491 |
| Initial urea (mg/dL) | 79.2 | 61.4 | 86.2 | 59.6 | 0.236 |
| ALT (UI/L) | 523.5 | 1261.7 | 71.0 | 112.5 | 0.212 |
| Billirubine (mg/dL) | 1.8 | 1.6 | 1.8 | 2.4 | 0.667 |
| Extracorporeal circuit volume/weight of patient (ml/kg) | 8.6 | 4.6 | 8.8 | 5.3 | 0.982 |
|
Hypotension Number % |
Hypotension Number % |
||||
| Age | <12 m | >12 m | |||
| 24 | 31.6 | 29 | 30.2 | 0.847 | |
| Sex | Male | Female | |||
| 34 | 33 | 19 | 27.5 | 0.446 | |
| Weight | <10 kg | >10 kg | |||
| 27 | 30 | 35 | 31.7 | 0.809 | |
| Diagnoses | Cardiopathies | Rest of diagnoses | |||
| 31 | 32.6 | 22 | 28.6 | 0.566 | |
| Mechanical ventilation | Yes | No | |||
| 48 | 33.1 | 5 | 18.5 | 0.132 | |
| Vasoactive drugs | Yes | No | |||
| 42 | 30.9 | 11 | 30.6 | 0.970 | |
| Initial MAP | <55 mmHg | >55 mmHg | |||
| 24 | 38.1 | 25 | 27.5 | 0.164 | |
| Dose of adrenaline | > 0.6 μg/kg/min | > 0.6 μg/kg/min | |||
| 12 | 35.3 | 32 | 29.4 | 0.513 | |
| Filter surface | <0.3 m2 | >0.3 m2 | |||
| 21 | 33.3 | 32 | 24.4 | 0.586 | |
| Extracorporeal circuit volume/weight of patient | > 5 ml/kg | < 5 ml/kg | |||
| 36 | 32.1 | 10 | 22.2 | 0.217 | |
| Mortalilty | Yes | No | |||
| 24 | 38.7 | 29 | 26.4 | 0.095 | |
ALT = alanine transferase; CRRT = continuous renal replacement therapy; MAP = mean arterial pressure; PELOD = pediatric logistic organ dysfunction; PIM = pediatric index of mortality; PRIMS = pediatric risk of mortality; SD = standard deviation.