Table 1.
Characteristics of Participants in the Young Hearts 3 Study.
| Variable | All (412)* | Males (N=225) | Females (N=186) |
|---|---|---|---|
| Biochemical Variables | |||
| Homocysteine (µmol/l) | |||
| N | 401 | 220 | 180 |
| Median (25th–75th percentile) | 8.9 (7.5–10.9) | 9.2 (7.7–11.0) | 8.6 (7.4–11.0) |
| RBC folate (nmol/l) | |||
| N | 364 | 193 | 170 |
| Median (25th–75th percentile) | 644.1 (479.0–844.8) | 704.8 (543.6–888.7) | 562.9 (428.7–764.7) |
| Serum folate (nmol/l) | |||
| N | 352 | 192 | 159 |
| Median (25th–75th percentile) | 12.8 (9.6–18.9) | 12.4 (9.4–18.9) | 13.2 (9.6–19.1) |
| Lifestyle Variables | |||
| Current use of cigarettes (N, %) | |||
| Yes | 156 (38.1) | 84 (37.7) | 72 (38.7) |
| No | 253 (61.9) | 139 (62.3) | 114 (61.3) |
| Current use of alcohol (N, %) | |||
| Yes | 336 (81.8) | 192 (85.3) | 144 (77.4) |
| No | 75 (18.3) | 33 (14.7) | 42 (22.6) |
| Current use of multivitamin supplements (N, %) |
|||
| Yes | 93 (22.6) | 44 (19.6) | 49 (26.3) |
| No | 318 (77.4) | 181 (80.4) | 137 (73.7) |
| Genotypes | |||
| SLC19A1 c.80G>A (N, %) | |||
| GG | 122 (29.6) | 67 (29.8) | 55 (29.6) |
| GA | 219 (53.2) | 123 (54.7) | 95 (51.1) |
| AA | 71 (17.2) | 35 (15.6) | 36 (19.4) |
| MTHFR g.677C>T (N, %) | |||
| CC | 178 (43.5) | 99 (44.4) | 78 (42.2) |
| CT | 176 (43.0) | 100 (44.8) | 76 (41.1) |
| TT | 55 (13.4) | 24 (10.8) | 31 (16.8) |
*
Information on sex was not available for one subject.