Figure 2.

Effect of DR on life span using bacterial dilution. A, B) Serial dilution of OP50 showed significant increases in both mean (A) and maximum (B) life span of wild-type N2 worms. However, maximum life span of nlp-7 and cup-4 mutants was not affected by DR, and mean life span of these mutants was only moderately increased in worms with 5 × 10⁸ bacteria/ml. Data are means ± se of 3 independent experiments. C) Life-span curves of N2, nlp-7(tm2984), nlp-7(tm2990), and cup-4(ok837) mutants were compared between AL (1×10¹⁰ bacteria/ml) and DR (5×10⁸ bacteria/ml).