Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Feb;24(2):383–392. doi: 10.1096/fj.09-142984

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 FASEB

PMC Copyright notice

Figure 3. — Knockout of nlp-7 or cup-4 reduces life span and resistance to oxidative stress. A, B) Life span of nlp-7(tm2984) (A) and nlp-7(tm2990) (B) (P<0.01) decreased significantly compared with wild-type N2 worms. RNAi of cup-4 on nlp-7 mutants showed no effect on life span of either nlp-7 mutant. However, a further decrease in life span of nlp-7(tm2990) (B) by RNAi of skn-1 (Supplemental Table S5) was evident. C) Mean life span of cup-4(ok837) (17.5 d) was shorter than that of N2 (22.1 d). skn-1 RNAi (mean life span 16.3 d) further decreased the life span of cup-4(ok837), while nlp-7 RNAi had no effect on the life span of cup-4(ok837) (Supplemental Table S5). D) Paraquat-resistance assay of nlp-7(tm2984), nlp-7(tm2990), and cup-4(ok837). Resistance to oxidative stress caused by paraquat was reduced in nlp-7 or cup-4 mutants. Data are means of duplicates.