FIG. 8.

Relationship between major blood lymphocyte numbers and disease severity. The natural logarithms of the proportion of lymphocytes staining positively for CD4⁺, CD8⁺, or B cells in circulating blood samples of animals with paucibacillary disease were correlated with disease severity in this group (n = 5). Each point represents an individual animal except at disease severity rank 12, where n is equal to 2. ⁂, significant correlation between the natural log of the CD8 T-cell count and histopathology (P < 0.005). Data were fitted with polynomial regression curves: for CD4⁺, r² = 0.76; for CD8⁺, r² = 0.98; for B cells, r² = 0.78.