FIG. 9.

Relationship between Th2 cytokine expression and disease severity. The fold change in the level of IL-4 mRNA expression in the blood of paucibacillary diseased animals after PPDj stimulation was compared to disease severity (n = 5). The mean PCR amplification efficiencies were 2.01 and 1.99 for β₂-microglobulin and IL-4, respectively. Each point represents an individual animal. There was a significant correlation between cytokine expression and histopathology (P < 0.05). The data were fitted with an exponential trend line (r² = 0.94).