TABLE 3.

Characteristics of ETVr detected by HBV DR v3 among 13 patients at week 0, 24, 48, 72, 96, and 144

Case	Age (yr)	Sex	HBV genotype	ALT (IU/liter)			HBV DNA (copies/ml)			Wk			No. of wks ETVr to BT	LVDr at baseline	ETVr at baseline	ETVr emerged during therapy
				Baseline	Nadir	Peak	Baseline	Nadir	Peak	ETVr	BT	BTH
J20	34	M	C	82	22	131	7.6	4.5	7.4	<92a	92	100	<22	M180, V204	NDf	ILMF184, G202
J27	61	M	C	79	38	150	7.4	3.9	7	<128b	128	144	<32	M180, V204	ND	SCGA184
J30	43	M	C	95	21	108	7.6	4.6	6.8	48	76	92	28	I80, M180, V/I204	ND	G202
J33	43	M	C	69	21	199	7.6	5.1	7.1	96	116	128	18	I80, L173, M180, VI204	ND	(ILFM184),c G202
J37d	48	M	C	465	43	76	7.6	4.7	6	48	60	60	12	I80, M180, V204, I204	ND	G202
J39	59	M	C	35	22	82	7	4.6	8	72	108	128	36	M180, V204	ND	SCGA/ILFM184, G202
J40	28	M	C	149	15	398	5.3	3.6	6.6	−8	64	72	72	M180, V204	(G+C) 202	G202
J22	44	M	C	240	17	24	7.6	3.5	5.6	<140e	144	NO	<44	M180, I204	ND	G202
J28	45	M	B	43	15	23	6.9	5.5	6.5	0	144	NO	144	M180, V204	SCGA184, V233	SCGA184, V233
U72	47	F	C	29	25	44	7.5	3.8	5	<144	144	NO	<48	L + V80, M180, V204	ND	SCGA184, (S+G)202
H55	47	F	C	102	19	20	6.1	3	4.2	48	88	NO	40	V + I80, M180, V204	ND	ILFM184
J19	57	M	B	233	29	43	7.4	2.8	3.3	24	NO	NO	NO	V + 180, M180, I204	ND	G202
U42	52	M	A	135	36	50	>7.6	5.3	5.8	<80	NO	NO	NO	M180, V204	ND	SCGA184

^aNot tested during weeks 72 and 92.

^bNot tested during weeks 96 and 128.

^cILFM184 was detected at week 144.

^dSwitch to ADV/LVD at week 60.

^eNot tested during weeks 96 and 140.

^fND, not detected.