TABLE 1.
Drug and parameter | % of strains in each breakpoint category |
||
---|---|---|---|
Susceptible | Intermediate | Resistant | |
Levofloxacin | |||
MIC | 66 | 3 | 31 |
MPC | 18 | 42 | 40 |
Moxifloxacin | |||
MIC | 71 | 6 | 23 |
MPC | 57 | 9 | 34 |
Gemifloxacin | |||
MIC | 67 | 4 | 29 |
MPC | 14 | 28 | 58 |
The CLSI breakpoints (6) are as follows for the three drugs: for levofloxaxin, ≤2 μg/ml for susceptible, 4 μg/ml for intermediate, and ≥8 μg/ml for resistant; for moxifloxacin, ≤1 μg/ml for susceptible, 2 μg/ml for intermediate, and ≥4 μg/ml for resistant; for gemifloxacin, ≤0.125 μg/ml for susceptible, 0.25 μg/ml for intermediate, and ≥0.5 μg/ml for resistant.