TABLE 3.
Posaconazole dose (mg/kg) |
P value for the difference between treatment and control groups infected with the following isolatea: |
|||
---|---|---|---|---|
WT | M220I mutant | TR L98H mutant | G54W mutant | |
64 | <0.0001* | <0.0001* | <0.0001* | <0.0001* |
16 | <0.0001* | <0.0001* | 0.0209 | 0.0018* |
4 | <0.0001* | 0.0108 | 0.1554 | 0.0724 |
1 | 0.0068* | 0.0831 | 0.1554 | 0.0238 |
The Bonferroni Kp value for 4 multiple comparisons was 0.01. P values of ≤0.01, which indicate a significant difference in survival rates between treatment and control groups, are asterisked. WT, wild type.