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. 2009 Nov 30;54(2):749–756. doi: 10.1128/AAC.01101-09

FIG. 3.

FIG. 3.

Bortezomib reduces serum HBV DNA levels but not HBeAg and HBsAg secretion. (A and B) HBeAg, HBsAg, and HBV DNA levels in mouse serum 1, 2, 3, and 6 days after intravenous injection of 1 mg/kg bortezomib (3 mice per group). (C and D) HBeAg, HBsAg, and HBV DNA levels in mouse serum 24 h after a single dose of 0.2, 1, or 5 mg/kg bortezomib (4 mice per group). Data are displayed as expression levels relative to those for control mice that did not receive the drug. Error bars represent standard errors of the means, and P values indicate the results of Student's t test.