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. 2009 Nov 23;78(2):639–650. doi: 10.1128/IAI.01043-09

FIG. 1.

FIG. 1.

Stimulation of BMM by oral and intestinal microflora. BMM were stimulated with tissue homogenates derived from the oral cavity, small intestine (SI), and colon from different 3-, 7-, and 21-day-old mice (n = 7) or adult germfree (gf) mice. The amounts of IL-6 (A), CCL5 (B), and IL-10 (C) in culture supernatants were determined by enzyme-linked immunosorbent assay (ELISA). (D) Correlation between IL-6 and CCL5 (•) levels and between IL-6 and IL-10 levels (○). (E) Correlation between total bacterial number and levels of CCL5 (•) and IL-10 (○). (F) Secretion of CXCL1 by mesothelial cells stimulated with tissue homogenates from the indicated sites from 3-, 7-, and 21-day-old B6 mice. The amounts of CXCL1 in culture supernatants were determined by ELISA. Each symbol represents mean value of triplicate cultures from individual mice. The standard deviations (SD) of triplicate cultures for individual mice averaged less than 19%. Bars denote mean values. *, P < 0.001.